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Search Results for " microtubule inhibitor 4 "

12

Compounds

Cat No. Product Name Synonyms Targets
T62642 Microtubule inhibitor 4
Microtubule inhibitor 4 (compound 2) is a potent inhibitor of microtubule and inhibits microtubule protein polymerization, HT-29 cells (IC50: 2.1 nM) exhibited cytotoxicity.
T15141 DM4 Ravtansine Others , Microtubule Associated
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
T2937 4'-Demethylepipodophyllotoxin 4'-DMEP,4-Demethylepipodophyllotoxin,DMEP,4'-O-demethylepipodophyllotoxin Microtubule Associated
4'-Demethylepipodophyllotoxin (DMEP) is a potent inhibitor of microtubule assembly.
T6212 Combretastatin A4 CA4,CRC 87-09 Microtubule Associated
Combretastatin A4 (CA4) is a microtubule-targeting agent that binds β-tubulin (Kd: 0.4 μM).
T13298 Verubulin hydrochloride MPC-6827 hydrochloride Microtubule Associated
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 brea...
T15576 Indibulin ZIO 301,D 24851 Apoptosis , Microtubule Associated
Indibulin (D 24851) is a synthetic small molecule with antimitotic and potential antineoplastic activities.Indibulin an orally applicable inhibitor of tubulin assembly, shows potent anticancer activity with a minimal neu...
T11947 MARK4 inhibitor 1 Apoptosis , Others , AMPK
MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.
T11184 EML4-ALK kinase inhibitor 1 EML4 ALK kinase inhibitor 1,EML4-​ALK kinase inhibitor 1 ALK
EML4-ALK kinase inhibitor 1 (EML4 ALK kinase inhibitor 1) is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
T15612 JH-VIII-157-02 Microtubule Associated , ALK
JH-VIII-157-02 is an inhibitor of ALK and inhibits echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) with IC50s of 2 nM for EML4-ALK G1202R, EML4-ALKwt, EML4-ALK C1156Y, EML4-ALK F1174L, and EML4-ALK F1174L...
T62118 KIF18A-IN-4
KIF18A-IN-4 is a moderately potent non-competitive KIF18A inhibitor of ATP and microtubule with an IC50 of 6.16 μM. KIF18A-IN-4 selectively acts on a large number of mitotic kinesins and kinases, with no direct effect on...
T62251 MARK-IN-4
MARK-IN-4 is a potent inhibitor of microtubule affinity-regulated kinase (MARK) (IC50: 1 nM). Inhibition of MARK is a potentially attractive approach to block neurofibrillary tangles in Alzheimer's disease.
T79232 MARK4 inhibitor 2 AMPK
MARK4 Inhibitor 2 is a potent inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4), exhibiting a Kₘ of 6.3×10⁷ and an IC₅₀ of 0.82 μM. It effectively inhibits the growth of human cells, thereby offering potentia...
TargetMol